TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

alkylating agent [1 record]

Record 1 2023-04-28

English

Subject field(s)
  • Biochemistry
  • Pharmacodynamics
  • Cancers and Oncology
DEF

A substance which introduces an alkyl radical into a compound in place of a hydrogen atom.

CONT

Alkylating agents contain alkyl radicals that attach themselves to the molecules of protein, nucleic acids, and amino acids in cells. Among the alkylating agents are the nitrogen mustards, ... the ethylenimines ... and the alkyl sulfonates ...

CONT

Cancer chemotherapy is an increasingly important aspect of drug treatment. Alkylating agents (that work by impairing cell division) and antimetabolites ... are used cytotoxically to attack malignant cells.

French

Domaine(s)
  • Biochimie
  • Pharmacodynamie
  • Cancers et oncologie
DEF

Substance synthétique, utilisée dans la chimiothérapie du cancer et présentant 2 ou 3 chaînes de la série alcoyle, qui dénature les nucléoprotéines et provoque une altération du noyau cellulaire et des chromosomes.

Key term(s)
  • agent alkoylant
  • alkoylant

Spanish

Campo(s) temático(s)
  • Bioquímica
  • Farmacodinámica
  • Tipos de cáncer y oncología
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