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antithymocyte globulin [1 record]

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Record 1 2014-04-07

English

Subject field(s)
  • Medication
  • Immunology
CONT

Antithymocyte globulin (ATG) is a concentrated anti-human T-lymphocyte immunoglobulin preparation derived from rabbits after immunization with a T-lymphoblast cell line. ATG is an immunosuppressive product for the prevention and treatment of acute rejection following organ transplantation. ATG reduces the host immune response against tissue transplants or organ allografts.

CONT

Immunosuppressive therapy with antithymocyte globulin (ATG) plus cyclosporine is an effective alternative to stem-cell transplantation and improves blood counts and survival. Although horse ATG is the standard therapy, rabbit ATG is more potent in depleting peripheral-blood lymphocytes and is preferred in other clinical circumstances.

French

Domaine(s)
  • Médicaments
  • Immunologie
Key term(s)
  • globuline anti-thymocyte
  • globuline anti-thymocytaire

Spanish

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