TERMIUM Plus®

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chloroquine phosphate [1 record]

Record 1 2011-02-08

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
C18H32CIN3O8P2
formula, see observation
50-63-5
CAS number
CONT

Chloroquine phosphate is in a class of drugs called antimalarials and amebicides. It is used to prevent and treat malaria. It is also used to treat amebiasis.

OBS

Chemical formula: C18H32CIN3O8P2

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
C18H32CIN3O8P2
formula, see observation
50-63-5
CAS number
CONT

Phosphate de chloroquine. Mécanismes d'action. Le mécanisme précis de l'activité antipaludéenne reste à préciser; serait analogue à celui de la quinine: forme un complexe avec les nucléoprotéines (ADN), entrainant une inhibition de la biosynthèse d'ADN et d'ARN, empêche l'incorporation du phosphore dans l'ADN et l'ARN, diminue la fixation active d'oxygène par le plasmodium, agit sur la forme érythrocytaire asexuée de tous les plasmodium (schizonticide).

OBS

Formule chimique : C18H32CIN3O8P2

Spanish

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