TERMIUM Plus®

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complement system [2 records]

Record 1 2006-02-27

English

Subject field(s)
  • Genetics
DEF

Any of a dozen different blood proteins that collectively form an essential part of the immune system: when faced with foreign cells, these proteins are activated one after the other, in a domino-like effect, eventually forming rings which punch crippling holes in the cell-membranes of the interlopers. This is a good thing in the case of a bacterial invader, but less desirable when it happens to a transplanted organ.

OBS

Compare with properdin.

Key term(s)
  • complement system
  • factor D
  • complement-blocking drug
  • anti-complement protein

French

Domaine(s)
  • Génétique

Spanish

Campo(s) temático(s)
  • Genética
Save record 1

Record 2 2003-06-03

English

Subject field(s)
  • Immunology
DEF

A group of nine plasma proteins that interact with each other, with antibodies, and with membranes to cause lysis of foreign cells or bacteria.

French

Domaine(s)
  • Immunologie
CONT

Le rejet de greffons s'accompagne de prolifération de l'intima. Chez l'animal on peut induire des lésions de type athéroscléreux par des conflits immunologiques. Chez l'homme des arguments existent : - l'activation du système du complément accompagne les grands mécanismes de l'athérosclérose et active à la fois l'endothélium et les monocytes; - les complexes immuns ont le même rôle et peuvent se déposer dans l'intima; des anticorps anti-lipoprotéines ont été décrits; - Les lymhocytes semblent avoir un rôle non négligeable, souligné récemment, dans leur relation avec les cytokines.

Spanish

Campo(s) temático(s)
  • Inmunología
DEF

Grupo de nueve enzimas básicas del suero que se activan cuando coinciden un anticuerpo y su antígeno.

OBS

Contribuyen a la destrucción de corpúsculos ajenos al cuerpo.

Save record 2

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