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early-after depolarization [1 record]

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Record 1 2017-04-06

English

Subject field(s)
  • Pharmacodynamics
CONT

In experimental models, amiodarone abolishes the generation of early-after depolarizations whereas other agents such as sotalol produce these depolarizations.

French

Domaine(s)
  • Pharmacodynamie
CONT

L'automaticité est la propriété d'une fibre d'initier un influx spontanément sans besoin d'une stimulation précédente. L'activité déclenchée est initiée par des influx appelés potentiels de basse amplitude, dépolarisation transitoire ou post-potentiels oscillants. Ces dépolarisations peuvent survenir avant (pendant la phase 3) ou après la repolarisation complète de la fibre. Elles sont au mieux appelées post-dépolarisations précoces ou tardives. Renseignement obtenu du Centre de recherches de l'Hôpital Sacré-Cœur de Montréal.

Spanish

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