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zalcitabine [1 record]
Record 1 - internal organization data 2006-05-24
Record 1, English
Record 1, Subject field(s)
- Medication
Record 1, Main entry term, English
- zalcitabine
1, record 1, English, zalcitabine
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- 2',3'-dideoxycytidine 1, record 1, English, 2%27%2C3%27%2Ddideoxycytidine
former designation
- ddC 1, record 1, English, ddC
former designation
- HIVID 1, record 1, English, HIVID
trademark, see observation
Record 1, Textual support, English
Record number: 1, Textual support number: 1 OBS
HIVID is the Hoffmann-La Roche brand of zalcitabine [formerly called 2',3'-dideoxycytidine (ddC)], a synthetic pyrimidine nucleoside analogue active against the human immunodeficiency virus (HIV). HIVID is available as film-coated tablets for oral administration in strengths of 0.375 mg and 0.750 mg. 1, record 1, English, - zalcitabine
Record 1, French
Record 1, Domaine(s)
- Médicaments
Record 1, Main entry term, French
- zalcitabine
1, record 1, French, zalcitabine
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- didésoxycytidine 2, record 1, French, did%C3%A9soxycytidine
former designation, feminine noun
- ddC 2, record 1, French, ddC
former designation, feminine noun
- ddC 2, record 1, French, ddC
- Hivid 1, record 1, French, Hivid
trademark
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
La zalcitabine est un analogue de synthèse d'un nucléoside naturel, la 2'-désoxycytidine, dont le groupement hydroxyde en position 3' a été remplacé par un atome d'hydrogène. Dans la cellule, la zalcitabine est convertie par un système enzymatique en son métabolite actif, le didésoxycytidine-5'-triphosphate (ddCTP), qui remplace le substrat naturel, le désoxycytidine-triphosphate (dCTP), de la transcriptase inverse du VIH et qui inhibe la réplication in vitro du VIH-1 en inhibant la synthèse de l'ADN viral. 2, record 1, French, - zalcitabine
Record number: 1, Textual support number: 2 OBS
Zalcitabine. (anciennement appelée didésoxycytidine (ddC)). 2, record 1, French, - zalcitabine
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Medicamentos
Record 1, Main entry term, Spanish
- dideoxicitidina
1, record 1, Spanish, dideoxicitidina
feminine noun
Record 1, Abbreviations, Spanish
- ddC 1, record 1, Spanish, ddC
feminine noun
Record 1, Synonyms, Spanish
- zalcitabina 1, record 1, Spanish, zalcitabina
feminine noun
- Hivid 1, record 1, Spanish, Hivid
masculine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 OBS
Principio activo del ddC, cuyo nombre comercial es Hivid. 1, record 1, Spanish, - dideoxicitidina
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