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antigène HLA-DR [1 record]

Record 1 1993-02-19

English

Subject field(s)
  • Immunology
CONT

Human leukocyte antigen ... governed by genes of the HLA complex (the human major histocompatibility complex), a region of the short arm of chromosome 6 containing several genetic loci, each having multiple alleles. Loci are designated by letters, HLA-A, -B, -C, -DP, -DQ, -DR (there are at least three sub-loci in the D region), -MB, MT, and Te, and alleles at each locus by numbers, e.g., HLA-A1, provisional designations being indicated by "w" (for "workshop"), e.g., HLA-DRw10....

French

Domaine(s)
  • Immunologie
CONT

Les antigènes HLA-DR [...] sont présents sur un faible nombre de cellules de l'organisme : les lymphocytes B, les lymphocytes T activés, notamment par la PHA et les lymphocytes T cytotoxiques, les macrophages, les cellules endothéliales des vaisseaux, les cellules épidermiques et les spermatozoïdes. Les études ont montré qu'ils étaient codés par un locus proche du locus HLA-D d'où leur dénomination d'antigènes DR (D related).

Spanish

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