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TIPIV [1 record]

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Record 1 2021-04-20

English

Subject field(s)
  • Human Diseases - Various
  • Blood
  • Immunology
CONT

The researchers who studied the German and Austrian patients ... had initially called the syndrome vaccine-induced prothrombotic immune thrombocytopenia; [two teams of researchers] now suggest a slightly simpler name: vaccine-induced immune thrombotic thrombocytopenia (VITT).

OBS

... the patients had unusual antibodies that trigger clotting reactions, which use up the body's platelets and can block blood vessels, leading to potentially deadly strokes or embolisms. The symptoms resemble a rare reaction to the drug heparin, called heparin-induced thrombocytopenia (HIT), in which the immune system makes antibodies to a complex of heparin and a protein called platelet factor 4 (PF4), triggering platelets to form dangerous clots throughout the body.

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
  • Immunologie

Spanish

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