TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

BRONZED DISEASE [1 record]

Record 1 2010-11-23

English

Subject field(s)
  • Human Diseases - Various
  • Hormones
  • Urinary Tract
  • Immunology
DEF

An adrenocortical insufficiency due to the destruction or dysfunction of the entire adrenal cortex [affecting] both glucocorticoid and mineralocorticoid function.

CONT

In 1855, Thomas Addison first described adrenal insufficiency, which was subsequently named after him. The basis of Addison disease has dramatically changed since its initial description. Originally, the disease usually resulted from an infection of the adrenal gland; the most common infection was tuberculosis, which is still the predominant cause of Addison disease in developing countries. Currently, in developed countries, Addison disease most commonly results from nonspecific autoimmune destruction of the adrenal gland.

OBS

Addison's disease ... is characterized by a bronzelike pigmentation of the skin and mucous membranes, anemia, weakness, and low blood pressure.

French

Domaine(s)
  • Maladies humaines diverses
  • Hormones
  • Appareil urinaire
  • Immunologie
CONT

La maladie d'Addison est une maladie rare due à une atteinte des glandes corticosurrénales conduisant à un déficit total en aldostérone et en cortisol. C'est un médecin anglais, Thomas Addison, qui décrivit ses premiers cas d'insuffisance surrénale lente par destruction bilatérale des surrénales. [...] Autrefois, la maladie était due surtout à la tuberculose. À l'heure actuelle, on souligne la fréquence des atteintes auto-immunes (les anticorps produits par le système immunitaire attaquent les glandes surrénales). [Elle se caractérise notamment par] une pigmentation brunâtre de la peau, des plis de flexions, des zones de frottement (d'où le nom de maladie bronzée) et des muqueuses.

Spanish

Campo(s) temático(s)
  • Enfermedades humanas varias
  • Hormonas
  • Vías urinarias
  • Inmunología
DEF

[Enfermedad que] se caracteriza por la pigmentación bronceada de la piel, postración grave y anemia progresiva. Es debida a la hipofunción de las glándulas suprarrenales y termina generalmente por la muerte.

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