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RSK [2 records]

Record 1 1996-10-17

English

Subject field(s)
  • Biochemistry
  • Genetics
CONT

Insoluble peptidoglycan(PGN) from staphylococcal cell walls as well as soluble PGN(sPGN) secreted by staphylococci in the presence of beta-lactam antibiotics induced TNF-alpha mRNA and secretion of bioactive TNF-alpha in the murine RAW264. 7 macrophage cell line. PGN and sPGN also induced rapid and dose-dependent tyrosine phosphorylation of several cellular proteins, including lyn and mitogen-activated protein kinases(extracellular signal-regulated kinases; but not hck, fgr, or vav) and increased the activities of mitogen-activated protein and rsk kinases. These PGN-and sPGN-induced effects were qualitatively similar to the effects induced by ReLPS, but higher concentrations of PGN and sPGN than ReLPS were required.

OBS

The Journal of Immunology: Volume: 155 Number: 05 Pages: 2620 - 2630 September 1, 1995.

French

Domaine(s)
  • Biochimie
  • Génétique

Spanish

Save record 1

Record 2 1996-01-05

English

Subject field(s)
  • Geographical Names

French

Domaine(s)
  • Noms géographiques

Spanish

Save record 2

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