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ACIDIC FIBROBLAST GROWTH FACTOR [1 record]
Record 1 - internal organization data 2001-11-22
Record 1, English
Record 1, Subject field(s)
- Molecular Biology
Record 1, Main entry term, English
- acidic fibroblast growth factor
1, record 1, English, acidic%20fibroblast%20growth%20factor
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- FGF-A 2, record 1, English, FGF%2DA
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Human acidic fibroblast growth factor (FGF) is perhaps the broadest specificity mitogen known. It stimulates a variety of cell types to divide. It also is chemotactic for many cell types (i.e. responsive cells migrate towards the source of the growth factor). Particularly responsive are vascular endothelial cells, thus FGF is also a potent angiogenic factor (causes the growth of blood vessels.). FGF plays a role in all stages of life. In embryogenesis, for example, FGF is important in organogenesis (the development of organs). In an adult, FGF is important in the wound healing process. Furthermore, aberrant regulation of FGF or its receptor(s) appears to be responsible for certain tumors within the brain and breast. 2, record 1, English, - acidic%20fibroblast%20growth%20factor
Record 1, French
Record 1, Domaine(s)
- Biologie moléculaire
Record 1, Main entry term, French
- facteur de croissance fibroblastique acide
1, record 1, French, facteur%20de%20croissance%20fibroblastique%20acide
correct, masculine noun
Record 1, Abbreviations, French
- FGF acide 2, record 1, French, FGF%20acide
correct, masculine noun
Record 1, Synonyms, French
- facteur de croissance des fibroblastes acide 3, record 1, French, facteur%20de%20croissance%20des%20fibroblastes%20acide
correct, masculine noun
- facteur acide de croissance des fibrobles 4, record 1, French, facteur%20acide%20de%20croissance%20des%20fibrobles
correct, less frequent
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les premières descriptions de facteurs de croissance de fibroblastes datent des années 1974-78. [...] Il s'agit du FGF basique et FGF acide, deux polypeptides chimiquement très proches, l'un de 146, l'autre de 140 acides aminés. Tous les deux sont des mitogènes puissants pour la plupart des tissus, dérivés du mésoderme et neuroectoderme. 3, record 1, French, - facteur%20de%20croissance%20fibroblastique%20acide
Record 1, Spanish
Record 1, Textual support, Spanish
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