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AGGRESOME [1 record]

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Record 1 2017-07-07

English

Subject field(s)
  • Molecular Biology
DEF

An aggregate sink of insoluble misfolded proteins in the endoplasmic reticulum or close to the microtubule organizing center containing chaperones, proteasomes and proteasome activator complexes.

French

Domaine(s)
  • Biologie moléculaire
DEF

Agrégat cytoplasmique de protéines mal repliées et accumulées en si grande quantité que le protéasome ne peut plus les hydrolyser.

CONT

[...] il a été montré que des agrégats de protéasomes et de substrats ubiquitylés du protéasome, appelés «aggrésomes», se formaient à ce niveau, suite à une inhibition du protéasome ou à une surexpression de substrats du protéasome.

OBS

agrésome : terme et définition publiés au Journal officiel de la République française le 14 juin 2017.

Spanish

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