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ALDEHYDE DEHYDROGENASE [1 record]
Record 1 - internal organization data 2011-03-28
Record 1, English
Record 1, Subject field(s)
- Biochemistry
Record 1, Main entry term, English
- aldehyde dehydrogenase
1, record 1, English, aldehyde%20dehydrogenase
correct
Record 1, Abbreviations, English
- ALDH 2, record 1, English, ALDH
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Aldehyde dehydrogenases are a group of enzymes that catalyse the oxidation (dehydrogenation) of aldehydes. Multiple forms exist in mammals in the cytosol, mitochondria and endoplasmic reticulum. They have been classified as Class 1 (cytosolic), Class 2 (mitochondrial) and Class 3 (tumour and other isozymes). 3, record 1, English, - aldehyde%20dehydrogenase
Record number: 1, Textual support number: 2 CONT
[Aldehyde dehydrogenases are] isoenzymes important in cell defence against both exogenous and endogenous aldehydes. 4, record 1, English, - aldehyde%20dehydrogenase
Record number: 1, Textual support number: 1 PHR
Fatty, liver mitochondrial, long-chain, mammalian aldehyde dehydrogenase. 5, record 1, English, - aldehyde%20dehydrogenase
Record 1, French
Record 1, Domaine(s)
- Biochimie
Record 1, Main entry term, French
- aldéhyde déshydrogénase
1, record 1, French, ald%C3%A9hyde%20d%C3%A9shydrog%C3%A9nase
correct, masculine noun
Record 1, Abbreviations, French
- ALDH 2, record 1, French, ALDH
correct, masculine noun
Record 1, Synonyms, French
- aldéhyde-déshydrogénase 3, record 1, French, ald%C3%A9hyde%2Dd%C3%A9shydrog%C3%A9nase
correct, masculine noun, less frequent
- déshydrogénase aldéhydique 4, record 1, French, d%C3%A9shydrog%C3%A9nase%20ald%C3%A9hydique
feminine noun, rare
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les aldéhydes déshydrogénases sont des flavoprotéines hépatiques qui captent les aldéhydes et les oxydent en acides. Il existe plusieurs isoenzymes catalysant ces réactions, dans le cytoplasme ou les mitochondries de nombreuses cellules : foie, rein, cerveau, globules rouges. Au cours de l'oxydation de l'acétaldéhyde, un coenzyme NAD+ est encore réduit, et l'acide acétique produit est lié au coenzyme A par une liaison riche en énergie. L'acétyl-CoA issu de ce métabolisme pénètre dans la mitochondrie devient un substrat du cycle de Krebs. 5, record 1, French, - ald%C3%A9hyde%20d%C3%A9shydrog%C3%A9nase
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Bioquímica
Record 1, Main entry term, Spanish
- deshidrogenasa aldehídica
1, record 1, Spanish, deshidrogenasa%20aldeh%C3%ADdica
correct, feminine noun
Record 1, Abbreviations, Spanish
- ALDH 2, record 1, Spanish, ALDH
correct, feminine noun
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
El fármaco más usado en Chile para el tratamiento del alcoholismo es el disulfiram, cuyo efecto se basa en inactivar covalentemente la deshidrogenasa aldehídica (ALDH), enzima que elimina el acetaldehído producido en el metabolismo del etanol. 2, record 1, Spanish, - deshidrogenasa%20aldeh%C3%ADdica
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