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ANTISENSE SEQUENCE [1 record]

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Record 1 1999-02-03

English

Subject field(s)
  • Genetics
CONT

Probes must contain the antisense sequence (complementary to the mRNA sequence). Double-stranded probes will of course always contain the antisense sequence. When designing single-stranded probes or probe templates, be sure that the antisense strand will be synthesized. Promoters or primers used to generate single-stranded antisense probes must be located at the more 3/ end of the coding sequence.

French

Domaine(s)
  • Génétique
CONT

Une autre approche développée par l'équipe de Jacques Hartzfeld de l'hôpital Paul-Brousse (Villejuif) consiste dans l'inactivation par des séquences antisens de gènes codant des facteurs maintenant les cellules souches dans un état quiescent, tels que le TGF (transforming growth factor)-ß1.

Spanish

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