TERMIUM Plus®

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BASIC MYELIN PROTEIN [1 record]

Record 1 2010-04-20

English

Subject field(s)
  • Biotechnology
  • Genetics
CONT

Viral infections trigger multiple sclerosis relapses: a prospective seroepidemiological study. A neurological surveillance was combined with prospective recording of upper respiratory and gastrointestinal infections and serological diagnosis of five common viral infections in 60 benign multiple sclerosis patients with a mean follow-up of 31 months... There was a significant correlation between adenovirus CF titre rises associated with upper respiratory tract infections and the occurrence of a major MS relapse in the AR period (n=7), while influenza infections were not followed by a major S relapse (n=6). Linear homologies have been demonstrated between adenovirus and basic myelin protein. The epidemiological approach is essential to our understanding of systemic antigens triggering multiple sclerosis activity.

French

Domaine(s)
  • Biotechnologie
  • Génétique
CONT

Environ deux millions de personnes dans le monde sont atteintes par la sclérose en plaques, l'une des maladies auto-immunes les plus graves et les plus répandues. Elle est due à la destruction des gaines de myéline par des lymphocytes T dont la cible principale est une séquence de 14 acides aminés de la "basic myelin protein" (BMP), l'une des protéines constitutives de la gaine de myéline.

Spanish

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