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The Government of Canada’s terminology and linguistic data bank.
CHIMERAPLAST [1 record]
Record 1 - internal organization data 2014-12-12
Record 1, English
Record 1, Subject field(s)
- Biotechnology
- Genetics
Record 1, Main entry term, English
- chimeric oligonucleotide
1, record 1, English, chimeric%20oligonucleotide
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- chimeraplast 2, record 1, English, chimeraplast
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
A sequence of DNA combined with RNA, used in a targeted repair process. These molecules bind to the target DNA. 3, record 1, English, - chimeric%20oligonucleotide
Record number: 1, Textual support number: 1 CONT
Direct skeletal muscle injection of the chimeric oligonucleotide into the cranial tibialis compartment of a six-week-old affected male dog, and subsequent analysis of biopsy and necropsy samples, demonstrated in vivo repair of the GRMD mutation that was sustained for 48 weeks. 1, record 1, English, - chimeric%20oligonucleotide
Record 1, French
Record 1, Domaine(s)
- Biotechnologie
- Génétique
Record 1, Main entry term, French
- oligonucléotide chimérique
1, record 1, French, oligonucl%C3%A9otide%20chim%C3%A9rique
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- chiméraplaste 2, record 1, French, chim%C3%A9raplaste
correct, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Un autre axe de recherche est la mise en œuvre des oligonucléotides chimériques qui sont formés par l'association d'un brin d'ADN [acide désoxyribonucléique] et d'un brin d'ARN [acide ribonucléique] complémentaires des régions chromosomiques à corriger. Cela permettra sans doute de réparer des mutations ponctuelles de gènes défectueux. 1, record 1, French, - oligonucl%C3%A9otide%20chim%C3%A9rique
Record number: 1, Textual support number: 2 CONT
Présent à forte concentration dans la cellule, l'oligonucléotide est qualifié de «chimérique», ou de «chiméraplaste», puisqu'il est constitué d'ADN [acide désoxyribonucléique] et d'ARN [acide ribonucléique], deux matériaux génétiques différents. 2, record 1, French, - oligonucl%C3%A9otide%20chim%C3%A9rique
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Biotecnología
- Genética
Record 1, Main entry term, Spanish
- oligonucleótido quimérico
1, record 1, Spanish, oligonucle%C3%B3tido%20quim%C3%A9rico
correct, masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- quimeroplasto 2, record 1, Spanish, quimeroplasto
correct, masculine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 CONT
Reparar el gen: Los intentos para reparar las mutaciones puntuales a nivel génico son hechos usando cortos oligonucleotidos quiméricos, que contienen tanto ARN [ácido ribonucleico] sobre una de las cadenas como ADN [ácido desoxirribonucleico] sobre la otra. La cadena de ADN de los oligonucleotidos quiméricos es perfectamente complementaria a la correcta secuencia génica del sitio de la mutación puntual del gen, mientras que la parte de ARN es perfectamente complementaria a la secuencia mutante. 1, record 1, Spanish, - oligonucle%C3%B3tido%20quim%C3%A9rico
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