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CIS-PLATINUM [1 record]

Record 1 2005-02-18

English

Subject field(s)
  • Medication
  • Cancers and Oncology
DEF

An antineoplastic ..., used in the treatment of metastatic testicular and ovarian cancer.

CONT

Often taken in conjunction with a platinum-based [anticancer] drug called cisplatin, doxorubicin significantly depresses the body's concentration of white blood cells. ... Women with ovarian cancer who receive optimally timed doses of doxorubicin and cisplatin are four times more likely to survive for five years than are women who receive the same drugs in ill-timed doses.

French

Domaine(s)
  • Médicaments
  • Cancers et oncologie
DEF

Composé inorganique du platine, utilisé en thérapeutique, comme anticancéreux, sous forme de diamine dichloro-platine-cis. (Le médicament est employé en perfusion pour le traitement des tumeurs de la sphère génitale, de la vessie et de la prostate. Il est contre-indiqué en cas d'atteinte de la fonction rénale, et il est également toxique pour la moelle osseuse, l'oreille et le tube digestif.)

CONT

Le cis-diamine-dichloro-platinum (sel de platinum) a eu bien du mal à trouver sa place en clinique : sa toxicité rénale a semblé longtemps le disqualifier. Ce handicap, non pas supprimé, mais surmonté par son administration au milieu d'une cure de diurèse, ses indications semblent le rapprocher des agents alkylants.

Spanish

Campo(s) temático(s)
  • Medicamentos
  • Tipos de cáncer y oncología
DEF

Fármaco alquilante antineoplásico.

OBS

Utilizado para el tratamiento germinal de testículo, carcinoma de ovario y en otros tumores genitourinarios: cérvix, endometrio, carcinoma de pulmón microcítico y no microcítico, carcinoma de cabeza y cuello, sarcoma de tejidos blandos.

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