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CONFORMATIONAL EXCHANGE [1 record]

Record 1 2011-04-05

English

Subject field(s)
  • Analytical Chemistry
  • Electromagnetic Radiation
CONT

Exchange (intermediate, fast, slow, chemical and conformational): Exchange is a kinetic process between two (or more) states that is characterized by a rate constant. In NMR [nuclear magnetic resonance] spectroscopy, exchange is classified into fast, intermediate and slow depending on the size of the rate constant with respect to chemical shift … Conformational exchange occurs when a structural element has more than one possible conformation. Chemical exchange is given when a chemical reaction is taking place, e.g. a ligand binds to the molecule that is measured or protons exchange with the solvent.

French

Domaine(s)
  • Chimie analytique
  • Rayonnements électromagnétiques
CONT

L’échange n’est pas un phénomène spécifique de la RMN [résonance magnétique nucléaire]. C’est un phénomène moléculaire réversible. On distingue essentiellement deux types d’échange : l’échange conformationnel et l’échange chimique. L’échange conformationnel n’implique aucune rupture de liaison mais simplement un changement de forme limité à un site particulier ou affectant l’ensemble de la molécule (ex : rotation d’un groupe méthyle autour de la liaison [sigma], inversion d’un cyclohexane).

Spanish

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