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DECAY ACCELERATING FACTOR [1 record]
Record 1 - internal organization data 2006-02-27
Record 1, English
Record 1, Subject field(s)
- Histology
Record 1, Main entry term, English
- decay accelerating factor 1, record 1, English, decay%20accelerating%20factor
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
DAF (decay accelerating factor) is expressed on erythrocytes and epithelial cells and inhibits the assembly on membranes of the classical pathway convertase and also accelerates its decay. Deficiency in DAF is associated with the disease paroxysmal nocturnal haemoglobinuria in which autologous erythrocytes become remarkably susceptible to lysis by complement. 1, record 1, English, - decay%20accelerating%20factor
Record 1, French
Record 1, Domaine(s)
- Histologie
Record 1, Main entry term, French
- protéine membranaire DAF
1, record 1, French, prot%C3%A9ine%20membranaire%20DAF
feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
[...] les protéines membranaires DAF et CR1 contrôlent la C3 convertase alterne. [...] Le «decay accelerating factor» (DAF) est formé d'une chaîne de 70 dKa particulière par l'existence d'un domaine glycolipidique permettant l'insertion membranaire et facilitant les mouvements rapides dans la membrane. [...] La distribution tissulaire du DAF est très large. Il est présent sur toutes les cellules sanguines, les cellules endothéliales et épithéliales. Le DAF dissocie les C3 convertases de manière très efficace et constitue un système de protection intrinsèque contre l'activation du complément par les cellules autologues. 1, record 1, French, - prot%C3%A9ine%20membranaire%20DAF
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Histología
Record 1, Main entry term, Spanish
- factor acelerador de la degradación
1, record 1, Spanish, factor%20acelerador%20de%20la%20degradaci%C3%B3n
correct, masculine noun
Record 1, Abbreviations, Spanish
- CD55 1, record 1, Spanish, CD55
correct, masculine noun
- DAF 1, record 1, Spanish, DAF
correct, masculine noun
Record 1, Synonyms, Spanish
- factor acelerador de la descomposición 1, record 1, Spanish, factor%20acelerador%20de%20la%20descomposici%C3%B3n
correct, masculine noun
Record 1, Textual support, Spanish
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