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ENDOPEPTIDASE [1 record]
Record 1 - internal organization data 2003-11-19
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
- Biotechnology
Record 1, Main entry term, English
- endopeptidase
1, record 1, English, endopeptidase
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Trivial name for a group of peptidase enzymes that catalyze the hydrolysis of interior peptide bonds in polypeptide chains. 2, record 1, English, - endopeptidase
Record number: 1, Textual support number: 1 CONT
Because chymotrypsin is secreted into the small intestine, it was first thought to be specific for the hydrolysis of relatively long polypeptides formed by the action of pepsin on ingested proteins in the stomach, but later work revealed that chymotrypsin can also attack short peptides. Tests of various synthetic peptides as substrates showed that the enzyme is an endopeptidase, i.e., it can split certain types of peptide linkages wherever they occur in a peptide chain, in contrast to the exopeptidases, which can split only terminal peptide bonds. 3, record 1, English, - endopeptidase
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
- Biotechnologie
Record 1, Main entry term, French
- endopeptidase
1, record 1, French, endopeptidase
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Nom générique des enzymes telles que la pepsine et la trypsine, capables d'attaquer les liaisons peptidiques centrales [...] d'un polypeptide. 2, record 1, French, - endopeptidase
Record number: 1, Textual support number: 1 CONT
L'hydrolyse des protéides peut se faire à l'aide d'acides, soit en solution bouillante, ce qui provoque une hydrolyse acide totale, soit en solution à 30 ou 40° C pendant 24 à 72 heures, ce qui conduit à une hydrolyse acide partielle libérant des oligopeptides. D'autre part, il existe une hydrolyse enzymatique (la plus importante pour les organismes vivants) sous l'action de protéinases de deux types : les endopeptidases qui coupent des liaisons peptidiques privilégiés à l'intérieur du protéide, et les exopeptidases dont le rôle est de découper la protéide en polypeptides à partir d'une extrémité de la molécule. 3, record 1, French, - endopeptidase
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Ciencias biológicas
- Biotecnología
Record 1, Main entry term, Spanish
- endopeptidasa
1, record 1, Spanish, endopeptidasa
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Cada una de las enzimas de la clase hidrolasas que catalizan la escisión de uniones peptídicas en posiciones interiores de las proteínas. 2, record 1, Spanish, - endopeptidasa
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