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FIBRIN-BOUND PLASMINOGEN [1 record]

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Record 1 1988-03-22

English

Subject field(s)
  • Biochemistry
CONT

TPA [tissue-type plasminogen activator] has been highly publicized as being the ideal thrombolytic agent because of its affinity for activating fibrin-bound plasminogen and not circulating plasminogen.

French

Domaine(s)
  • Biochimie
CONT

La sélectivité d'action du t-PA sur la fibrine pourrait également être expliqué par la présence à son extrémité N-terminale, d'une succession de 43 acides aminés responsables de l'affinité pour la fibrine et qui sont retrouvés dans la molécule de fibronectine mais qui manquent dans la molécule d'UK.

Spanish

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