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FIBROBLAST GROWTH FACTOR [1 record]

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Record 1 2001-11-12

English

Subject field(s)
  • Molecular Biology
CONT

Fibroblast growth factors (FGFs) are essential molecules for mammalian development, wound healing, and when inappropriately expressed, cancer. Engineered mutations in the genes encoding several FGFs and FGF receptors (FGFRs) result in developmental defects and/or embryonic lethality. Additionally, point mutations in the genes encoding FGFRs 1, 2 and 3 result in human hereditary craniofacial and skeletal dysplasias.

French

Domaine(s)
  • Biologie moléculaire
CONT

Lorsque ces cellules sont soumises à l'action d'un facteur de croissance connu sous le nom de FGF (fibroblast growth factor) acide, les cellules se dispersent, migrent activement et adoptent une morphologie que l'on peut qualifier de fibroblastique, puisque les cellules s'allongent, s'aplatissent et émettent des pseudopodes.

OBS

Terme tiré de la base de données PASCAL.

Spanish

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