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The Government of Canada’s terminology and linguistic data bank.
GENE ADDITION [1 record]
Record 1 - internal organization data 2008-10-28
Record 1, English
Record 1, Subject field(s)
- Genetics
- Biotechnology
Record 1, Main entry term, English
- gene addition
1, record 1, English, gene%20addition
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- addition of genes 2, record 1, English, addition%20of%20genes
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
Until now, gene therapy researchers have focused on gene addition, using a variety of modified viruses as vectors or transport vehicles to "infect" and insert the proper genetic material into cell nuclei that have genes with undesirable mutations. 1, record 1, English, - gene%20addition
Record 1, French
Record 1, Domaine(s)
- Génétique
- Biotechnologie
Record 1, Main entry term, French
- addition de gènes
1, record 1, French, addition%20de%20g%C3%A8nes
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- addition génique 2, record 1, French, addition%20g%C3%A9nique
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Forme de thérapie génique consistant en l'administration d'un gène correcteur, soit par injection ou inhalation de vecteurs adénoviraux ou de vecteurs synthétiques in vivo, soit par la modification de l'ADN d'une cellule prélevée puis réimplantée dans un patient. 3, record 1, French, - addition%20de%20g%C3%A8nes
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Genética
- Biotecnología
Record 1, Main entry term, Spanish
- adición génica
1, record 1, Spanish, adici%C3%B3n%20g%C3%A9nica
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
- adición de genes 2, record 1, Spanish, adici%C3%B3n%20de%20genes
correct, feminine noun
- introducción de genes 3, record 1, Spanish, introducci%C3%B3n%20de%20genes
correct, feminine noun
- inserción de genes 4, record 1, Spanish, inserci%C3%B3n%20de%20genes
correct, feminine noun
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Adición de una copia funcional de un gen al genoma de un organismo. 5, record 1, Spanish, - adici%C3%B3n%20g%C3%A9nica
Record number: 1, Textual support number: 1 CONT
La introducción de genes a través de vectores se basa en la tecnología del ADN recombinante. Lo primero que se hace es cortar el "pedazo" de molécula de interés (el gen terapéutico) [...] Entonces se corta el gen terapéutico y el vector con la misma enzima de restricción [...] Posteriormente el gen es introducido a la célula por el mecanismo intrínseco de cada vector. Hay diferentes tipos de vectores víricos: Retrovirus, Adenovirus, Parvovirus, Herpesvirus. 3, record 1, Spanish, - adici%C3%B3n%20g%C3%A9nica
Record number: 1, Textual support number: 2 CONT
Terapia genética: la inserción de genes normales o alterados genéticamente dentro de las células, a menudo para reemplazar genes defectuosos en especial en el tratamiento de desórdenes genéticos. 4, record 1, Spanish, - adici%C3%B3n%20g%C3%A9nica
Record number: 1, Textual support number: 3 CONT
Los plásmidos [...] son usados como vectores dada la facilidad con [que] pueden ser "abiertos" y su corto mensaje natural, características que permiten la adición de genes extraños y aún entonces su reinserción en sus bacterias de origen donde se replicarán expresando las instrucciones añadidas. 6, record 1, Spanish, - adici%C3%B3n%20g%C3%A9nica
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