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GUINEA PIG MAXIMIZATION TEST [1 record]

Record 1 2016-11-17

English

Subject field(s)
  • Scientific Research Methods
  • Medication
CONT

The guinea pig has been the animal of choice for predictive sensitisation tests for several decades. Two types of tests have been developed: adjuvant tests in which sensitisation is potentiated by the injection of Freund's complete adjuvant (FCA), and non-adjuvant tests. ... In this updated version, the guinea pig maximisation test (GPMT) of Magnusson and Kligman which uses adjuvant ... and the non-adjuvant Buehler Test ... are given preference over other methods.

French

Domaine(s)
  • Méthodes de recherche scientifique
  • Médicaments
CONT

Depuis plusieurs décennies, le cobaye représente l'animal de prédilection pour les essais visant à prévoir la sensibilisation. Deux types d'essai ont été élaborés : les essais avec adjuvant, dans lesquels la sensibilisation est potentialisée par l'injection de l'Adjuvant Complet de Freund (ACF), et les essais sans adjuvant. [...] Dans cette version mise à jour, parmi les méthodes, on donne la préférence au test de maximisation chez le cobaye (GPMT) de Magnusson et Kligman, qui utilise un adjuvant [...] et au test de Buehler, qui n'utilise pas d'adjuvant [...]

Spanish

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