TERMIUM Plus®

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HEAT DENATURATION [1 record]

Record 1 2000-11-08

English

Subject field(s)
  • Biochemistry
DEF

Loss of structural conformation of a molecule by heating. Proteins and nucleic acids can be readily denatured by heating (as, for example, when the white of an egg hardens on boiling). Denaturation of nucleic acids is used in technology involving hybridization and also in determining Cot values.

OBS

Melting is used specifically for nucleic acids.

French

Domaine(s)
  • Biochimie
DEF

Modification de la structure native tridimensionnelle d'une macromolécule par la chaleur. p. 63; NOBIO 1987, p. 71)

OBS

Le terme fusion est spécifiquement employé pour les acides nucléiques.

Spanish

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