TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

LIGAND [2 records]

Record 1 2006-11-07

English

Subject field(s)
  • Chemistry
DEF

A molecule, ion, or atom that is attached to the central atom of a coordination compound, a chelate, or other complex.

CONT

The Lewis Theory has been used extensively in the interpretation of the formation of coordination compounds in which the ligand is the base and the metal ion or ligand acceptor is the acid.

OBS

Apart from its conventional usage in complexometry and with chelating ion exchange columns the word ligand is employed in affinity chromatography with reference to the biospecific material which is coupled to the polymetric carrier to form the biospecific column.

French

Domaine(s)
  • Chimie
DEF

Atome, ion ou molécule associé à l'atome central dans un complexe.

CONT

Nous désignons par «coordinat» un atome, ou groupement d'atomes, chargé ou non, intervenant dans la formation de la liaison coordinative.

PHR

Ligand ambidentate, hexadentate, monodentate, multidentate, polydentate, tétradentate, tridentate, unidentate; ligand dur, mou; ligand axial, donneur, pontant.

PHR

Métal-ligand.

Spanish

Campo(s) temático(s)
  • Química
Save record 1

Record 2 2003-12-10

English

Subject field(s)
  • Molecular Biology
DEF

A molecule that binds to another molecule, used especially to refer to a small molecule that binds specifically to a larger molecule, e.g., an antigen binding to an antibody, a hormone or neurotransmitter binding to a receptor, or a substrate or allosteric effector binding to an enzyme.

CONT

The immobilization of a ligand is carried out by the carrier-binding method in many cases ... Immobilization of a ligand on a carrier should be carried out via a reactive group in the ligand molecule which does not participate in affinity binding with the substance to be purified, as in the case of immobilization of enzymes.

French

Domaine(s)
  • Biologie moléculaire
CONT

Les enzymes allostériques [...] possèdent sur chaque monomère plusieurs sites spécifiques, dits sites allostériques, pour la fixation de différents ligands, dont le substrat. En se fixant sur l'enzyme, ces ligands entraînent une modification de la configuration du site de fixation du substrat. Ils facilitent ou défavorisent la liaison du substrat à l'enzyme, agissant comme régulateur du fonctionnement de l'enzyme. On dit qu'il existe un effet de coopérativité entre les sites.

Spanish

Campo(s) temático(s)
  • Biología molecular
Save record 2

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