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MULTISUBUNIT ENZYME [1 record]
Record 1 - internal organization data 2011-01-07
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
Record 1, Main entry term, English
- multisubunit enzyme
1, record 1, English, multisubunit%20enzyme
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- subunit enzyme 2, record 1, English, subunit%20enzyme
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The terminology used to describe the structure of multisubunit enzymes is as follows. A protein composed of a number of subunits is called an oligomeric protein, or an oligomer. The subunits building the oligomeric structure are referred to as protomers, monomers, or subunits ... Some regulatory proteins are composed of identical subunits such as in glyceraldehyde-3-phosphate dehydrogenase, or from nonidentical subunits as in the case of hemoglobin ... Most oligomeric proteins are composed of a small number of subunits which form closed oligomeric structures that rarely contain more than 12 subunits ... Minor changes in primary structure ... result in the formation of additional intramolecular intersubunit electrostatic or hydrophobic bonds. Even a small number of these bonds can drastically increase the stability of subunit enzymes. 2, record 1, English, - multisubunit%20enzyme
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
Record 1, Main entry term, French
- enzyme oligomère
1, record 1, French, enzyme%20oligom%C3%A8re
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Certaines enzymes sont constituées d'une seule chaîne polypeptidique; il s'agit le plus souvent d'enzymes sécrétées telle la ribonucléase par exemple. D'autres, en beaucoup plus grand nombre, sont formées de plusieurs chaînes (ou sous-unités) identiques ou différentes. Lorsque les enzymes comprennent des sous-unités identiques, chacune des chaînes est bien entendu porteuse d'un centre actif : une enzyme tétramérique a 4 centres actifs. Dans cette catégorie on trouve les enzymes allostériques (qui représentent 10-20 % des enzymes à structure quaternaire). 1, record 1, French, - enzyme%20oligom%C3%A8re
Record 1, Spanish
Record 1, Textual support, Spanish
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