TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

NISOLDIPINE [1 record]

Record 1 2010-11-16

English

Subject field(s)
  • Chemical Elements and Compounds
  • Medication
Universal entry(ies)
63675-72-9
CAS number
C20H24N2O6
formula, see observation
CONT

Nisoldipine, a dihydropyridine calcium-channel blocker, is used alone or with an angiotensin-converting enzyme inhibitor, to treat hypertension, chronic stable angina pectoris, and Prinzmetal's variant angina. Nisoldipine is similar to other peripheral vasodilators. Nisoldipine inhibits the influx of extra cellular calcium across the myocardial and vascular smooth muscle cell membranes possibly by deforming the channel, inhibiting ion-control gating mechanisms, and/or interfering with the release of calcium from the sarcoplasmic reticulum.

OBS

Active ingredient commonly sold under the name Sular.

OBS

Chemical formula: C20H24N2O6

French

Domaine(s)
  • Éléments et composés chimiques
  • Médicaments
Entrée(s) universelle(s)
63675-72-9
CAS number
C20H24N2O6
formula, see observation
CONT

Des canaux calciques potentiel-dépendants ont récemment été découverts dans des cellules de Kupffer isolées [...], et la nisoldipine, un inhibiteur calcique, diminue la phagocytose des particules dans le foie de rat conservé [...]

OBS

Principe actif couramment commercialisé sous le nom de Sular.

OBS

Formule chimique : C20H24N2O6

Spanish

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