TERMIUM Plus®

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NO EFFECT DOSE [1 record]

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Record 1 2008-11-24

English

Subject field(s)
  • Pharmacodynamics
CONT

Teratology and genetic counselors are frequently asked whether very low exposures of drugs and chemicals can cause a child's congenital malformations. One critical factor on which the counseling is based is the dose. Because teratogenic effects follow a toxicologic dose-response curve with a no-effect dose, frequently counselors can refute a causal relationship because the dose was far below the no-observable-effect dose.

Key term(s)
  • no effect dose

French

Domaine(s)
  • Pharmacodynamie
DEF

Quantité maximale de substance toxique qui peut être ingérée par un animal quotidiennement, pendant toute sa vie, sans provoquer de troubles physiologiques (en mg/Kg de poids corporel).

Spanish

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TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
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