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POLYCLONAL ANTIBODY [1 record]

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Record 1 2003-06-10

English

Subject field(s)
  • Biotechnology
  • Molecular Biology
CONT

To investigate whether passive transfer of antibodies to viral glycoproteins would protect against herpes simplex virus type 2-induced stromal keratitis, Balb/c mice were infected on the scarified cornea with herpes simplex virus types 1 or 2 (HSV-1 and HSV-2, respectively) and monoclonal et polyclonal antibodies were administered intraperitoneally 24 hr later.

French

Domaine(s)
  • Biotechnologie
  • Biologie moléculaire
CONT

Un dosage immunométrique était donc envisageable. Il a été mis au point en produisant, d'une part des anticorps polyclonaux à partir d'un immunogène constitué par la partie N-terminale du peptide (six acides aminés) couplé à un porteur antigénique et, d'autre part, un anticorps monoclonal dirigé contre la partie C-terminale de la substance P spécifique des cinq derniers acides aminés.

Spanish

Campo(s) temático(s)
  • Biotecnología
  • Biología molecular
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