TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

PROXIMAL TUBULE DIURETIC [1 record]

Record 1 2023-05-01

English

Subject field(s)
  • Medication
  • Urinary Tract
CONT

Proximal convoluted tubule diuretics. The proximal convoluted tubule is the primary site for NA+ [sodium ion] reabsorption and seems a likely site for effective diuretic action. However, the number of downstream reabsorption sites limits the effectiveness of any diuretic targeting this region. Carbonic anhydrase inhibitors are the only commonly used diuretics that particularly target this region although they are rarely used primarily as diuretics. They work by blocking the enzyme carbonic anhydrase, which acts to help reabsorb bicarbonate in the proximal tubule.

OBS

Acetazolamide is an example of a proximal diuretic.

French

Domaine(s)
  • Médicaments
  • Appareil urinaire
CONT

Les diurétiques proximaux : ce sont les inhibiteurs de l'anhydrase carbonique (acétazolamide) et les substances osmotiques (mannitol).

Spanish

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