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Record 1 1994-08-09

English

Subject field(s)
  • Pharmacodynamics
CONT

Clinical trials have shown that clozapine helps about 30 percent of those schizophrenic patients who do not respond to other antipsychotic medications or who develop intolerable side effects. This drug's unusual properties, such as its specific interaction with certain dopamine and serotonin receptors (D4 and 5HT2), may help in the effort to understand schizophrenia itself.

French

Domaine(s)
  • Pharmacodynamie
CONT

Des essais cliniques ont montré que la clozapine soulage environ 30 pour cent des patients schizophrènes insensibles à d'autres médicaments antipsychotiques ou qui souffrent d'effets secondaires intolérables. Les propriétés remarquables de cette substance, telle son interaction spécifique avec certains récepteurs de la dopamine et de la sérotonine (D4 et 5HT2), améliorent notre compréhension de la maladie.

Spanish

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