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SPLICE VARIANT [1 record]

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Record 1 2022-01-04

English

Subject field(s)
  • Genetics
  • Molecular Biology
CONT

Alternative splicing is a highly regulated process with the potential to express a splice variant only under specific spatio-temporal conditions.

CONT

Splice variants play an important role within the cell in both increasing the proteome diversity and in cellular function. Splice variants are also associated with disease states and may play a role in their etiology.

French

Domaine(s)
  • Génétique
  • Biologie moléculaire
CONT

Grâce à [l'épissage alternatif], plusieurs ARNm [acides ribonucléiques messagers] peuvent être produits à partir d'un même gène. Ces variants d'épissage se distinguent par leur contenu en exons.

Spanish

Campo(s) temático(s)
  • Genética
  • Biología molecular
CONT

Una variante de empalme del gen producía la proteína AIB1-Delta4, que resultó ser la responsable de promover la comunicación y el reclutamiento de las células circundantes, lo que finalmente conduce a la metástasis.

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