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THROMBIN [1 record]
Record 1 - internal organization data 2011-06-07
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
Record 1, Main entry term, English
- thrombin
1, record 1, English, thrombin
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
An enzyme with proteolytic activity that catalyzes the conversion of fibrinogen to fibrin during the clotting of blood. It is formed from an inactive precursor, prothrombin, in the presence of blood platelets, calcium ions and thromboplastin. 2, record 1, English, - thrombin
Record number: 1, Textual support number: 1 CONT
Under the action of thrombin, which splits off a small peptide from fibrinogen, fibrinogen is activated and starts to interact with other monomers. The end-to-end association forms long fibrin fibrils, but apparently there is also some lateral staggering and cross-linking with other fibers to form a network. As clotting progresses, aided by the blood platelets, fibrin retracts, squeezing out the serum, and the blood clot is completed. 2, record 1, English, - thrombin
Record number: 1, Textual support number: 1 OBS
Fibrinogenase and thrombase are obsolete terms. 3, record 1, English, - thrombin
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
Record 1, Main entry term, French
- thrombine
1, record 1, French, thrombine
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Enzyme catalysant l'hydrolyse de la fibrinogène en fibrine, provoquant ainsi la coagulation du sang. 2, record 1, French, - thrombine
Record number: 1, Textual support number: 1 CONT
L'ensemble du processus de coagulation du sang est fort complexe. Il met en jeu des ions calcium et une dizaine de facteurs protéiques qui font l'objet d'une activation en cascade, le plus souvent par des réactions de protéolyse partielle. C'est ainsi que la thrombine, qui transforme le fibrinogène, provient elle-même de l'activation d'une glycoprotéine plasmatique, la prothrombine. 3, record 1, French, - thrombine
Record number: 1, Textual support number: 1 OBS
Thrombose, plasmase, thrombosine et fibrine-ferment sont des termes vieillis à éviter. 2, record 1, French, - thrombine
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Ciencias biológicas
Record 1, Main entry term, Spanish
- trombina
1, record 1, Spanish, trombina
correct, feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
Record number: 1, Textual support number: 1 DEF
Enzima proteolítica que hidroliza específicamente enlaces peptídicos con L-arginina. Convierte fibrinógeno en fibrina y se forma a partir del precursor inactivo protrombina. 2, record 1, Spanish, - trombina
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