TERMIUM Plus®

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TOP-DOWN MAPPING [1 record]

Record 1 1996-10-17

English

Subject field(s)
  • Biotechnology
CONT

In top-down mapping, a single chromosome is cut (with rare-cutter restriction enzymes) into large pieces, wich are ordered and subdivided; the smaller pieces are then mapped further. The resulting macro-restriction maps depict the order of and distance between sites at which rare-cutter enzymes cleave.

French

Domaine(s)
  • Biotechnologie
OBS

[...] dans la stratégie dite de «haut en bas» les YAC sont utilisés directement pour l'hybridation in situ sur des chromosomes. On peut repérer leur emplacement sur les chromosomes et procéder à la cartographie sur une grande distance d'une région chromosomique donnée.

Spanish

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