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TRANSCRIPTION FACTOR IIA [1 record]

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Record 1 2011-11-07

English

Subject field(s)
  • Genetics
CONT

The X-ray crystal structure of the transcription factor IIA (TFIAA) in complex with TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 angstrom resolution. TFIIA is composed of ß-barrel and a four-helix bundle motif that together have a boot-like appearance.The ß-barel extends the TBP ß-sheet and bridges over the DNA major groove immediately upstream of the TATA box.

French

Domaine(s)
  • Génétique

Spanish

Campo(s) temático(s)
  • Genética
CONT

TFIIA tiene 3 subunidades en humanos. Se une a TBP [proteína de unión a la caja TATA] y estabiliza su unión al DNA.

OBS

TFIIA por sus siglas en inglés.

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