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TRANSFORMING GROWTH FACTOR ALPHA [1 record]

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Record 1 1991-07-01

English

Subject field(s)
  • Cytology
CONT

Transforming growth factor alpha in arterioles: cell surface processing of its precursor by elastases.

OBS

Tiré de: Molecular and cellular biology, 1990, 10 (9), 4596-4602.

French

Domaine(s)
  • Cytologie
CONT

Le TGF a qui présente une forte homologie avec l'epidermal growth factor stimule l'angiogénèse in vivo et est mitogène pour les cellules endothéliales. Le TGF B entraîne in vivo, après injection sous-cutanée, une accumulation de macrophages, de fibroblastes et de collagène; et induit une néovascularisation. En revanche, in vitro, il inhibe la croissance des cellules endothéliales. Son activité angiogénique in vivo met donc probablement en jeu les macrophages.

Spanish

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