TERMIUM Plus®

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VIRUS-ENCODED PROTEIN [1 record]

Record 1 1996-10-02

English

Subject field(s)
  • Biochemistry
  • Molecular Biology
DEF

A 96-amino acid (14 kd) protein, which is incorporated into the virion. It interacts with the p6gag part of the Pr55gag precursor. the Vpr detected in the cell is localized to the nucleus. Proposed funtions for Vpr include the nuclear import of preintegration complexes, cell growth arrest, transactivation of cellular genes, and induction of cellular differentiation. Found in HIV-1, HIV-2, SIVmac and SIVmnd, It is homologous to VPX of SIVmgm.

OBS

Glossary of molecular biology (portions of the glossary text were taken directly or modified from definitions in the U.S. Congress Office of Technology Assessment document).

French

Domaine(s)
  • Biochimie
  • Biologie moléculaire
CONT

Le processus de transcription inverse commence pendant l'encapsidation de l'ARN. Il n'est pas initié par un ARN de transfert, comme chez les rétrovirus, mais par une protéine virale qui n'est autre que la polymérase.

OBS

Équivalents français approuvés par l'Unité de recherche en vaccinologie, Laboratoire et Service d'infectiologie, Centre hospitalier de l'université Laval (CHUL), Québec.

Spanish

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