TERMIUM Plus®

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WET GRANULATION [1 record]

Record 1 2008-02-14

English

Subject field(s)
  • Pharmaceutical Manufacturing
CONT

The general steps involved in a wet granulation process are : 1. The powdered ingredients are weighed and mixed intimately by geometric dilution. 2. The granulating solution or binder is prepared. 3. The powders and the granulation solution are kneaded to proper consistency. 4. The wet mass is forced through a screen or wet granulator. 5. The granules are dried in an oven or a fluidized bed dryer. 6. The dried granules are screened to a suitable size for compression. 7. A lubricant and a disintegrating agent are mixed with the granulation. 8. The granulation is compressed into the finished tablet.

French

Domaine(s)
  • Fabrication des produits pharmaceutiques
CONT

Dans la granulation par voie humide, les ingrédients actifs et les excipients sont mouillés avec une solution aqueuse ou contenant des solvants pour donner des granulés grossiers à particules de grand calibre. Ces granulés sont séchés, mélangés à des lubrifiants (stéarate de magnésium), des désintégrants ou liants, puis transformés en comprimés par compression.

Spanish

Campo(s) temático(s)
  • Fabricación de productos farmacéuticos
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