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ACETATE CYPROTERONE [1 record]

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Record 1 1994-04-12

English

Subject field(s)
  • Medication

French

Domaine(s)
  • Médicaments
OBS

La cyprotérone est une molécule stéroïde qui a démontré 2 propriétés distinctes en clinique: d'une part, une propriété antiandrogénique: la cyprotérone bloque la fixation de la dihydrotestostérone, le métabolite actif de la testostérone, aux récepteurs spécifiques de la cellule prostatique cancéreuse [...] D'autre part, une propriété progestative et antigonadotrope: la cyprotérone exerce une rétroaction négative sur l'axe hypothalamo-hypophysaire en inhibant la sécrétion de LH, ce qui entraîne la diminution de la production de testostérone testiculaire.

Spanish

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