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MALADIE HEREDITAIRE MONOGENIQUE [1 record]

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Record 1 1997-03-20

English

Subject field(s)
  • Genetics
CONT

The foundation for our current studies has been a detailed investigation of the molecular genetics of retinoblastoma, a paradigm for familial cancer predisposition and a classic monogenic hereditary disease.

OBS

monogenic character: a character determined by a single gene.

French

Domaine(s)
  • Génétique
CONT

Surtout, on entrevoit de claires indications à la thérapie génique. À côté des maladies héréditaires monogéniques, où l'on compte quelques succès (déficit ADA, mucopolysaccharidoses) et des échecs temporaires (muscovidose), l'intérêt de la thérapie génique s'est vite déplacée vers les maladies acquises polygéniques comme le cancer.

OBS

Génétique moléculaire.

Spanish

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