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TRANSFERT CHROMOSOMES MEDIATION MICROCELLULAIRE [1 record]
Record 1 - internal organization data 2011-11-02
Record 1, English
Record 1, Subject field(s)
- Genetics
Record 1, Main entry term, English
- microcell-mediated chromosome transfer
1, record 1, English, microcell%2Dmediated%20chromosome%20transfer
correct
Record 1, Abbreviations, English
- MMCT 2, record 1, English, MMCT
correct
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
A new potentially interesting resource has been described in the abstract by Vojta et al.: Subchromosomal transferable fragments (STFs). These are generated starting from the chromosome 1-only interspecific hybrid using futher fragmentation by means of the combination of the random integration of a retroviral vector bearing a selectable marker, and gamma irradiation, by means of several steps of microcell mediated chromosome transfer and selective propagation in mouse A9 cells. 3, record 1, English, - microcell%2Dmediated%20chromosome%20transfer
Record 1, French
Record 1, Domaine(s)
- Génétique
Record 1, Main entry term, French
- procédé MMCT
1, record 1, French, proc%C3%A9d%C3%A9%20MMCT
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- transfert de chromosomes à médiation microcellulaire 2, record 1, French, transfert%20de%20chromosomes%20%C3%A0%20m%C3%A9diation%20microcellulaire
proposal, masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
Les vecteurs les plus sophistiqués, les YAC [...], ont permis récemment l'introduction de 1000 mégabases. MJ Mendez et al. ont tout simplement introduit dans les cellules ES, grâce à un procédé, le microcell-mediated chromosome transfer (MMCT), des chromosomes entiers. Des cellules hybrides hommes-souris possédant, chacune, un chromosome humain ont d'abord été sélectionnées puis fractionnées en «microcellules». Celles-ci ont été fusionnées aux cellules ES qui ont alors été introduites dans des embryons précoces de souris, réimplantés ultérieurement dans des femelles pseudogestantes. 1, record 1, French, - proc%C3%A9d%C3%A9%20MMCT
Record 1, Spanish
Record 1, Textual support, Spanish
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