TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

5-FU [2 records]

Record 1 2006-07-28

English

Subject field(s)
  • Biochemistry
  • Cancers and Oncology
DEF

... a chemotherapy drug that is given as a treatment for some types of cancer ...

French

Domaine(s)
  • Biochimie
  • Cancers et oncologie
OBS

Fluorouracil. [Il] freine la mitose cellulaire, prend la place de l'uracile dans les désoxyribonucléotides. Le désoxyribonucléotide du 5-FU inhibe la thymidilate synthétase (TS) empêchant la méthylation de l'acide désoxyridylique en acide thymidylique et interfère donc dans la biosynthèse de l'ADN.

Spanish

Campo(s) temático(s)
  • Bioquímica
  • Tipos de cáncer y oncología
DEF

Fármaco antimetabolito antineoplásico.

OBS

[...] utilizado en el tratamiento adyuvante quimioterapéutico del carcinoma de mama y colon, y el tratamiento de éstos y otros carcinomas [...] en etapas avanzadas.

Save record 1

Record 2 2006-03-30

English

Subject field(s)
  • Chemical Elements and Compounds
  • Biochemistry
  • Medication
  • Cancers and Oncology
CONT

5-fluorouracil is an approved anti-cancer drug that works by preventing normal cell division. In its intravenous formulation it is used to treat a number of tumours including breast cancer and cancer of the colon. It also comes as a cream which can be used to treat cervical, anal or genital neoplasms caused by human papilloma virus (HPV). ... 5-fluorouracil is also known as fluorouracil, or the abbreviation 5-FU. It is available in a generic formulation and is also manufactured by Roche under the tradename Efudix.

Key term(s)
  • 5 FU
  • 5FU

French

Domaine(s)
  • Éléments et composés chimiques
  • Biochimie
  • Médicaments
  • Cancers et oncologie
CONT

[...] le fluorouracile est un antimétabolite très utilisé en chimiothérapie anticancéreuse. Il a été développé à partir de l'uracile, base azotée qui entre dans la composition de l'ADN. Un atome de fluor remplace un atome d'hydrogène en position 5, d'où le nom de 5-fluorouracile ou encore 5FU. Le fluorouracile est un antimétabolite qui «mime» l'uracile, précurseur de la thymine, base nécessaire à la synthèse d'ADN et composant des ARN.

Key term(s)
  • 5 FU
  • 5-FU

Spanish

Campo(s) temático(s)
  • Elementos y compuestos químicos
  • Bioquímica
  • Medicamentos
  • Tipos de cáncer y oncología
DEF

Fármaco antimetabolito antineoplásico.

OBS

[...] utilizado en el tratamiento adyuvante quimioterapéutico del carcinoma de mama y colon, y el tratamiento de éstos y otros carcinomas [...] en etapas avanzadas.

Save record 2

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