TERMIUM Plus®

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GB3 [1 record]

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Alphabetical list of terms

Record 1 2009-08-25

English

Subject field(s)
  • Chemical Elements and Compounds
  • Biochemistry
DEF

[A lipid belonging to] a specific family of glycosphingolipids ...

CONT

In the absence of sufficient alpha-galactosidase, ... lipids, particularly globotriaosylceramide (GL-3; also known as Gb3, ceramide trihexoside, and CTH), accumulate progressively in the lysosomes of many cell types throughout the body. GL-3 accumulation in renal endothelial cells may play a role in renal failure. ... Studies ... demonstrate that [the] treatment results in significant GL-3 reduction from the vascular endothelium of the kidney, heart, and skin and from certain other cell types.

Key term(s)
  • GL3

French

Domaine(s)
  • Éléments et composés chimiques
  • Biochimie
DEF

Lipide utilisé dans les parois des vaisseaux sanguins, des nerfs et de nombreux organes.

Spanish

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