TERMIUM Plus®

The Government of Canada’s terminology and linguistic data bank.

HEMOPHAGOCYTIC LYMPHOHISTIOCYTOSIS [1 record]

Filter results by subject field Alphabetical list of terms

Filter results by subject field

Alphabetical list of terms

Record 1 2023-03-30

English

Subject field(s)
  • Human Diseases - Various
  • Blood
DEF

... a disorder characterized by the abnormal accumulation of T lymphocytes and macrophages in normal tissues.

CONT

Hemophagocytic lymphohistiocytosis (HLH) is a rare but potentially fatal disease of normal but overactive histiocytes and lymphocytes that commonly appears in infancy, although it has been seen in all age groups. ... The pathological hallmark of this disease is the aggressive proliferation of activated macrophages and histiocytes, which phagocytose other cells, namely RBCs [red blood cells], WBCs [white blood cells], and platelets, leading to the clinical symptoms. The uncontrolled growth is nonmalignant and does not appear clonal ... The spleen, lymph nodes, bone marrow, liver, skin, and membranes that surround the brain and spinal cord are preferential sites of involvement.

PHR

Acquired, familial, primary, secondary hemophagocytic lymphohistiocytosis.

French

Domaine(s)
  • Maladies humaines diverses
  • Sang
DEF

Affection caractérisée par une accumulation anormale de lymphocytes T et de macrophages dans des tissus normaux.

CONT

Les lymphohistiocytoses hémophagocytaires (LH) se distinguent en primitives et secondaires. Dans le premier cas, la LH est liée à un déficit immunitaire primitif. Les LH secondaires sont liées à différents états pathologiques (infections en particulier, ainsi qu'affections néoplasiques et auto-immunes) qui aboutissent au tableau de LH à cause d'un déficit acquis des fonctions cytotoxiques des lymphocytes T et des cellules «natural killer».

PHR

Lymphohistiocytose hémophagocytaire familiale, primaire, primitive, secondaire.

Spanish

Save record 1

Copyright notice for the TERMIUM Plus® data bank

© Public Services and Procurement Canada, 2024
TERMIUM Plus®, the Government of Canada's terminology and linguistic data bank
A product of the Translation Bureau

Display options

Change the order of display of the official languages of Canada
Option to display the non-official languages (Spanish or Portuguese)
Display definitions, contexts, etc., on records

Features

Language Portal of Canada

Access a collection of Canadian resources on all aspects of English and French, including quizzes.

Writing tools

The Language Portal’s writing tools have a new look! Easy to consult, they give you access to a wealth of information that will help you write better in English and French.

Glossaries and vocabularies

Access Translation Bureau glossaries and vocabularies.

Date Modified: