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HOUSE-KEEPING FUNCTION [1 record]
Record 1 - internal organization data 1994-03-22
Record 1, English
Record 1, Subject field(s)
- Cytology
- Genetics
Record 1, Main entry term, English
- house-keeping function
1, record 1, English, house%2Dkeeping%20function
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The research project concerns characterization of the expression of the FMR-1 gene in various cultured cells under various conditions of growth or states of differentiation ... The production of isoform-specific antibodies is dependent on research to be performed on a grant [which focuses] on expression of this gene in human and mouse tissues, rather then in cultured cells ... The proposal that the FMR-1 gene has a house-keeping function is not consistent with the proposal that the gene is modulated during cellular growth and differentiations .... 1, record 1, English, - house%2Dkeeping%20function
Record number: 1, Textual support number: 2 CONT
Half-life of proteasomes (multiprotease complexes) in rat liver ... This finding together with the ubiquitous distribution of proteasomes in eukaryotic cells indicates that proteasomes belong to a family of proteins with house-keeping function [Source: PASCAL database]. 2, record 1, English, - house%2Dkeeping%20function
Record 1, Key term(s)
- housekeeping function
Record 1, French
Record 1, Domaine(s)
- Cytologie
- Génétique
Record 1, Main entry term, French
- fonction domestique
1, record 1, French, fonction%20domestique
proposal, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
Record 1, Textual support, French
Record number: 1, Textual support number: 1 OBS
Il s'agit d'un gène. Par inférence au terme fréquemment trouvé « gène domestique = house-keeping gene ». 1, record 1, French, - fonction%20domestique
Record number: 1, Textual support number: 2 OBS
[gènes domestiques :] Certains gènes ne s'expriment que dans certains tissus, c'est la base de la différenciation. D'autres codent pour des protéines ubiquitaires, indispensables à la survie de chaque cellule, comme par exemple les gènes des enzymes de la glycolyse, de la respiration et des métabolismes intermédiaires. Ces gènes, appelés gènes domestiques, ont en commun une série de caractéristiques : un taux de transcription en général faible et continu, ce qui n'exclut pas cependant une éventuelle régulation; l'absence de TATA box; une grande richesse en séquences CG hypo-méthylées. Les gènes domestiques sont précédés par et contiennent de très nombreuses répétitions du doublet CG [...] 2, record 1, French, - fonction%20domestique
Record 1, Spanish
Record 1, Textual support, Spanish
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