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LYMPHOBLASTOID CELL LINE [1 record]

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Record 1 1998-08-28

English

Subject field(s)
  • Lymphatic System
DEF

B cells immortalized by a transforming agent, generally Epstein -Barr virus, and thus capable of growing in continuous cultures.

French

Domaine(s)
  • Système lymphatique
CONT

Les chercheurs du laboratoire de J.L. Mandel à Strasbourg (INSERM,CNRS) en collaboration avec ceux du laboratoire d'Y. Agid (INSERM U 289) À l'Hôpital de la Pitié-Salpêtrière à Paris, viennent de publier dans la revue Nature (vol 378 : 403-406 du 23 XI 1995) un moyen de détecter, sur un gel d'électrophorèse, un nombre de triplets à partir duquel la pathologie se manifeste. Il s'agit d'un anticorps monoclonal qui reconnaît, sur un extrait cellulaire d'une lignée lymphoblastoïde provenant d'un patient atteint de chorée d'Huntington, un nombre de triplets supérieur de plus de 24 à celui de l'état normal.

Spanish

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