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NON-COMPETITIVE INHIBITION [1 record]
Record 1 - internal organization data 2011-08-09
Record 1, English
Record 1, Subject field(s)
- Biological Sciences
Record 1, Main entry term, English
- noncompetitive inhibition
1, record 1, English, noncompetitive%20inhibition
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- non-competitive inhibition 2, record 1, English, non%2Dcompetitive%20inhibition
correct
Record 1, Textual support, English
Record number: 1, Textual support number: 1 DEF
Inhibition of enzyme action based solely on the concentration of the inhibitor; substrate concentration is not a factor. The inhibitors combine with the enzyme on a site other than that utilized by the substrate. 2, record 1, English, - noncompetitive%20inhibition
Record number: 1, Textual support number: 1 CONT
In non-competitive inhibition the binding of the inhibitor substance is thought to induce a conformational change in the enzyme molecule which does not interfere with the attachment of the substrate to the active site, but which greatly reduces the catalytic activity of the enzyme. 2, record 1, English, - noncompetitive%20inhibition
Record 1, French
Record 1, Domaine(s)
- Sciences biologiques
Record 1, Main entry term, French
- inhibition non compétitive
1, record 1, French, inhibition%20non%20comp%C3%A9titive
correct, feminine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- inhibition par association non exclusive 2, record 1, French, inhibition%20par%20association%20non%20exclusive
correct, feminine noun
- inhibition non concurrentielle 2, record 1, French, inhibition%20non%20concurrentielle
correct, feminine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 DEF
Inhibition enzymatique où l'inhibiteur et le substrat n'ont pas de structures apparentées et l'inhibiteur se lie à un site différent de celui du substrat. Elle ne peut être renversée par des concentrations élevées du substrat. 2, record 1, French, - inhibition%20non%20comp%C3%A9titive
Record number: 1, Textual support number: 1 CONT
Le type le plus courant d'inhibition non compétitive est produit par les réactifs qui peuvent se fixer réversiblement, hors du site actif, sur un groupement fonctionnel de l'enzyme indispensable au maintien de la conformation tridimensionnelle active de la molécule enzymatique. Certains enzymes possédant un groupement -SH essentiel sont inhibés de façon non compétitive par les métaux lourds. Ces groupements -SH doivent donc être intacts pour que l'enzyme conserve sa conformation active normale. 3, record 1, French, - inhibition%20non%20comp%C3%A9titive
Record number: 1, Textual support number: 1 OBS
L'acétazolamide, diurétique fort utilisé, agit en inhibant de façon non compétitive l'anhydrase carbonique au niveau du rein. 4, record 1, French, - inhibition%20non%20comp%C3%A9titive
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Ciencias biológicas
Record 1, Main entry term, Spanish
- inhibición no antagónica
1, record 1, Spanish, inhibici%C3%B3n%20no%20antag%C3%B3nica
feminine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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