TERMIUM Plus®
The Government of Canada’s terminology and linguistic data bank.
PEAK EFFECT [1 record]
Record 1 - internal organization data 2023-05-25
Record 1, English
Record 1, Subject field(s)
- Pharmacology
Record 1, Main entry term, English
- peak effect
1, record 1, English, peak%20effect
correct
Record 1, Abbreviations, English
Record 1, Synonyms, English
- maximum drug response 2, record 1, English, maximum%20drug%20response
Record 1, Textual support, English
Record number: 1, Textual support number: 1 CONT
The peak effect [of a dose of drug] occurs when the receptors are maximally activated. This effect is largely determined by the rates of movement of the drug to the SOA [site of action] and removal of drug from the SOA. 3, record 1, English, - peak%20effect
Record number: 1, Textual support number: 2 CONT
Morphine is the prototypical opioid agonist and remains the gold standard to which other opioids are compared. However, morphine has several features that may render it less than ideal ... Morphine is relatively hydrophilic, causing a notoriously delayed peak effect (~15-20 minutes) even when given intravenously. ...The phenylpiperidine opioid subclass, fentanyl, and its congeners ... have pharmacokinetic profiles that may be more ideal for shorter surgical procedures ... All of these opioids are more potent than morphine and are quite lipophilic with very rapid onset approximating 30 to 60 minutes and peak effects within 5 minutes. 4, record 1, English, - peak%20effect
Record 1, French
Record 1, Domaine(s)
- Pharmacologie
Record 1, Main entry term, French
- effet maximal
1, record 1, French, effet%20maximal
correct, masculine noun
Record 1, Abbreviations, French
Record 1, Synonyms, French
- pic d'effet 2, record 1, French, pic%20d%27effet
masculine noun
Record 1, Textual support, French
Record number: 1, Textual support number: 1 CONT
La morphine, qui est un hydrophile, met plus de temps à atteindre son effet maximal que le fentanyl, qui est un opioïde lipophile. 3, record 1, French, - effet%20maximal
Record 1, Spanish
Record 1, Campo(s) temático(s)
- Farmacología
Record 1, Main entry term, Spanish
- efecto máximo
1, record 1, Spanish, efecto%20m%C3%A1ximo
masculine noun
Record 1, Abbreviations, Spanish
Record 1, Synonyms, Spanish
Record 1, Textual support, Spanish
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