TERMIUM Plus®

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PER PROTOCOL [1 record]

Record 1 2014-01-06

English

Subject field(s)
  • Scientific Measurements and Analyses
  • Scientific Research
  • General Medicine, Hygiene and Health
DEF

An analysis that excludes subjects who were not compliant with the intervention regimen (took prohibited concurrent treatments, for example).

OBS

The population of interest is thus highly filtered and not influenced by factors that could dilute the effect of treatment. This form of analysis may therefore produce a larger estimate of treatment effect.

OBS

If done alone, [per protocol analysis] leads to bias.

OBS

per protocol: term and definition standardized by the Health Technology Assessment (HTA) Glossary English Editorial Board and the Translation Bureau.

French

Domaine(s)
  • Mesures et analyse (Sciences)
  • Recherche scientifique
  • Médecine générale, hygiène et santé
DEF

Analyse d’où sont exclus les sujets qui n’ont pas respecté le protocole thérapeutique (ont pris des traitements concomitants interdits, par exemple).

OBS

La population étudiée est ainsi très filtrée et ne subit pas l’influence de facteurs susceptibles de diluer l’effet du traitement. Cette forme d’analyse risque donc d’augmenter l’effet estimé du traitement.

OBS

analyse selon le respect du protocole; analyse par protocole : termes et définition normalisés par l'Institut national d'excellence en santé et en services sociaux (INESSS) et le Bureau de la traduction.

Spanish

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